I have a Microsoft wireless laser 6000 v2 keyboard, and I cannot get the multimedia keys to work at all. I have tried all suggestions that I've seen in the forums (including a post from me requesting help), but quite honestly, it should not be so difficult. With v2.5, I had to use a third party tool called mmkeys.exe to make it work. that program does not work with 3.0.
I was using the free version before, but recently purchased the gold version so I can have a reasonable expectation that this will be resolved.